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Exploring Selectivity of Multikinase Inhibitors across the Human Kinome

[Image: see text] Selectivity of kinase inhibitors, or the lack thereof, continues to be an intensely debated topic in drug discovery research. Especially, type I inhibitors, which represent most of the currently available kinase inhibitors, are often thought to lack selectivity because they target...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Miljković, Filip, Bajorath, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130781/
https://ncbi.nlm.nih.gov/pubmed/30221217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01960
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