Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

A variety of innate immune responses and functions are dependent on time of day, and many inflammatory conditions are associated with dysfunctional molecular clocks within immune cells. However, the functional importance of these innate immune clocks has yet to be fully characterized. NRF2 plays a c...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Early, James O., Menon, Deepthi, Wyse, Cathy A., Cervantes-Silva, Mariana P., Zaslona, Zbigniew, Carroll, Richard G., Palsson-McDermott, Eva M., Angiari, Stefano, Ryan, Dylan G., Corcoran, Sarah E., Timmons, George, Geiger, Sarah S., Fitzpatrick, Darren J., O’Connell, Daniel, Xavier, Ramnik J., Hokamp, Karsten, O’Neill, Luke A. J., Curtis, Annie M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130388/
https://ncbi.nlm.nih.gov/pubmed/30127006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800431115
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