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Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X(4) in rat urothelial cells
Partial bladder outlet obstruction (pBOO) is a prevalent urological condition commonly accompanied by increased intravesical pressure, inflammation and fibrosis. Studies have demonstrated that pBOO results in increased NLRP3 inflammasome and caspase-1 activation and that ATP is released from urothel...
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| Udgivet i: | Int Urol Nephrol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129973/ https://ncbi.nlm.nih.gov/pubmed/30099658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11255-018-1948-0 |
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