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Cyclin A2 regulates symmetrical mitotic spindle formation and centrosome amplification in human colon cancer cells

Colon cancer is one of the most fatal cancers in the United States, and is characterized by the presence of chromosomal instability (CIN), causes of which are largely unclear. Emerging evidence indicates that abnormal spindle geometry and supernumerary centrosomes lead to CIN in cells. However, if a...

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Publicat a:Am J Transl Res
Autors principals: Li, Jun-An, Liu, Bai-Chun, Song, Ying, Chen, Xin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129552/
https://ncbi.nlm.nih.gov/pubmed/30210703
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