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Cyclin A2 regulates symmetrical mitotic spindle formation and centrosome amplification in human colon cancer cells

Colon cancer is one of the most fatal cancers in the United States, and is characterized by the presence of chromosomal instability (CIN), causes of which are largely unclear. Emerging evidence indicates that abnormal spindle geometry and supernumerary centrosomes lead to CIN in cells. However, if a...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Jun-An, Liu, Bai-Chun, Song, Ying, Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129552/
https://ncbi.nlm.nih.gov/pubmed/30210703
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