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Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C
Huntington’s disease (HD) is a neurodegenerative disease caused by a polyglutamine expansion in the huntingtin (Htt) protein. Mutant Htt causes synaptic transmission dysfunctions by interfering in the expression of synaptic proteins, leading to early HD symptoms. Synaptic vesicle proteins 2 (SV2s),...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129247/ https://ncbi.nlm.nih.gov/pubmed/29713895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-018-0230-x |
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