Frequent basal cell cancer development is a clinical marker for inherited cancer susceptibility

Innate DNA repair mechanisms play a critical role in protecting skin keratinocytes from UV mutagenesis and skin cancer development. We hypothesized that individuals who develop frequent skin cancers may harbor germline defects in DNA repair genes and have increased predisposition to internal maligna...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Cho, Hyunje G., Kuo, Karen Y., Li, Shufeng, Bailey, Irene, Aasi, Sumaira, Chang, Anne Lynn S., Oro, Anthony E., Tang, Jean Y., Sarin, Kavita Y.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129130/
https://ncbi.nlm.nih.gov/pubmed/30089731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122744
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