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Frequent basal cell cancer development is a clinical marker for inherited cancer susceptibility

Innate DNA repair mechanisms play a critical role in protecting skin keratinocytes from UV mutagenesis and skin cancer development. We hypothesized that individuals who develop frequent skin cancers may harbor germline defects in DNA repair genes and have increased predisposition to internal maligna...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Cho, Hyunje G., Kuo, Karen Y., Li, Shufeng, Bailey, Irene, Aasi, Sumaira, Chang, Anne Lynn S., Oro, Anthony E., Tang, Jean Y., Sarin, Kavita Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129130/
https://ncbi.nlm.nih.gov/pubmed/30089731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122744
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