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Structure and Gating Mechanism of the Transient Receptor Potential Channel TRPV3
The transient receptor potential (TRP) channel TRPV3 plays a crucial role in skin physiology and pathophysiology. Mutations in TRPV3 are associated with various skin diseases, including Olmsted syndrome, atopic dermatitis and rosacea. Here we present cryo-EM structures of full length mouse TRPV3 in...
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| Udgivet i: | Nat Struct Mol Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128766/ https://ncbi.nlm.nih.gov/pubmed/30127359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0108-7 |
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