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Dppa2/4 facilitate epigenetic remodeling during reprogramming to pluripotency
As somatic cells are converted into iPSCs, their chromatin is remodeled to a pluripotent configuration with unique euchromatin-to-heterochromatin ratio, DNA methylation patterns and enhancer/promoter status. The molecular machinery underlying this process is largely unknown. Here, we show that ESC-s...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Stem Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128737/ https://ncbi.nlm.nih.gov/pubmed/30146411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.08.001 |
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