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A Single XLF Dimer Bridges DNA Ends During Non-Homologous End Joining
Non-homologous end joining (NHEJ) is the primary pathway of DNA double-strand break repair in vertebrate cells, yet it remains unclear how NHEJ factors assemble a synaptic complex that bridges DNA ends. To address the role of XRCC4-like factor (XLF) in synaptic complex assembly, we employed single-m...
שמור ב:
| הוצא לאור ב: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128732/ https://ncbi.nlm.nih.gov/pubmed/30177755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0120-y |
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