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Ensemble and Single-Molecule Analysis of Non-Homologous End Joining in Frog Egg Extracts
Non-homologous end joining (NHEJ) repairs the majority of DNA double-strand breaks in human cells, yet the detailed order of events in this process has remained obscure. Here, we describe how to employ Xenopus laevis egg extract for the study of NHEJ. The egg extract is easy to prepare in large quan...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404771/ https://ncbi.nlm.nih.gov/pubmed/28645371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.03.020 |
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