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Two-Stage Synapsis of DNA Ends during Non-Homologous End Joining
Repair of DNA double-strand breaks (DSBs) is essential for genomic stability. The most common DSB repair mechanism in human cells, non-homologous end joining (NHEJ), rejoins broken DNA ends by direct ligation. It remains unclear how components of the NHEJ machinery assemble a synaptic complex that b...
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| 發表在: | Mol Cell |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4799494/ https://ncbi.nlm.nih.gov/pubmed/26990988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.010 |
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