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Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks
Hexavalent chromium [Cr(VI)] damages DNA and causes cancer, but it is unclear which DNA damage responses (DDRs) most critically protect cells from chromate toxicity. Here, genome-wide quantitative functional profiling, DDR measurements and genetic interaction assays in Schizosaccharomyces pombe reve...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128646/ https://ncbi.nlm.nih.gov/pubmed/30148840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007595 |
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