von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury

von Willebrand factor (VWF) is an adhesive ligand, and its activity is proteolytically regulated by the metalloprotease ADAMTS-13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat 13). An elevated level of plasma VWF has been widely considered a marker for endothelial cell activat...

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Bibliographic Details
Published in:Blood
Main Authors: Wu, Yingang, Liu, Wei, Zhou, Yuan, Hilton, Tristan, Zhao, Zilong, Wang, Min, Yeon, Jason, Houck, Katie, Thiagarajan, Perumal, Zhang, Fangyi, Shi, Fu-Dong, Wu, Xiaoping, Li, Min, Dong, Jing-fei, Zhang, Jianning
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2018
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128082/
https://ncbi.nlm.nih.gov/pubmed/29941674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-03-841932
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