Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

Cardiolipin (CL) is an anionic phospholipid located exclusively in the mitochondrial inner membrane. Its presence in blood indicates mitochondrial damage and release from injured cells. Here, we report the detection of CL-exposed brain-derived mitochondrial microparticles (mtMPs) at 17 547 ± 2677/μL...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Zhao, Zilong, Wang, Min, Tian, Ye, Hilton, Tristan, Salsbery, Breia, Zhou, Eric Z., Wu, Xiaoping, Thiagarajan, Perumal, Boilard, Eric, Li, Min, Zhang, Jianning, Dong, Jing-fei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2016
Θέματα:
Thrombosis and Hemostasis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891956/
https://ncbi.nlm.nih.gov/pubmed/27002118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-688838
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