Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

Cardiolipin (CL) is an anionic phospholipid located exclusively in the mitochondrial inner membrane. Its presence in blood indicates mitochondrial damage and release from injured cells. Here, we report the detection of CL-exposed brain-derived mitochondrial microparticles (mtMPs) at 17 547 ± 2677/μL...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood
Autors principals: Zhao, Zilong, Wang, Min, Tian, Ye, Hilton, Tristan, Salsbery, Breia, Zhou, Eric Z., Wu, Xiaoping, Thiagarajan, Perumal, Boilard, Eric, Li, Min, Zhang, Jianning, Dong, Jing-fei
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891956/
https://ncbi.nlm.nih.gov/pubmed/27002118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-688838
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars