Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

Cardiolipin (CL) is an anionic phospholipid located exclusively in the mitochondrial inner membrane. Its presence in blood indicates mitochondrial damage and release from injured cells. Here, we report the detection of CL-exposed brain-derived mitochondrial microparticles (mtMPs) at 17 547 ± 2677/μL...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Zhao, Zilong, Wang, Min, Tian, Ye, Hilton, Tristan, Salsbery, Breia, Zhou, Eric Z., Wu, Xiaoping, Thiagarajan, Perumal, Boilard, Eric, Li, Min, Zhang, Jianning, Dong, Jing-fei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2016
Konular:
Thrombosis and Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891956/
https://ncbi.nlm.nih.gov/pubmed/27002118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-688838
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