Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice

Coagulopathy is common in patients with traumatic brain injury (TBI) and predicts poor clinical outcomes. We have shown that brain-derived extracellular microvesicles, including extracellular mitochondria, play a key role in the development of TBI-induced coagulopathy. Here, we further show in mouse...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhou, Yuan, Cai, Wei, Zhao, Zilong, Hilton, Tristan, Wang, Min, Yeon, Jason, Liu, Wei, Zhang, Fangyi, Shi, Fu-Dong, Wu, Xiaoping, Thiagarajan, Perumal, Li, Min, Zhang, Jianning, Dong, Jing-fei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794502/
https://ncbi.nlm.nih.gov/pubmed/29162596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-801738
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