Combination of Asiatic Acid and Naringenin Modulates NK Cell Anti-cancer Immunity by Rebalancing Smad3/Smad7 Signaling

Transforming growth factor β1 (TGF-β1) plays a promoting role in tumor growth via a mechanism associated with hyperactive Smad3 and suppressed Smad7 signaling in the tumor microenvironment. We report that retrieving the balance between Smad3 and Smad7 signaling with asiatic acid (AA, a Smad7 inducer...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Lian, Guang-Yu, Wang, Qing-Ming, Tang, Patrick Ming-Kuen, Zhou, Shuang, Huang, Xiao-Ru, Lan, Hui-Yao
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127879/
https://ncbi.nlm.nih.gov/pubmed/30017880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.06.016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker