Asiatic Acid Inhibits Liver Fibrosis by Blocking TGF-beta/Smad Signaling In Vivo and In Vitro

Liver fibrosis is a major cause of liver failure, but treatment remains ineffective. In the present study, we investigated the mechanisms and anti-hepatofibrotic activities of asiatic acid (AA) in a rat model of liver fibrosis induced by carbon tetrachloride (CCl(4)) and in vitro in TGF-beta1-stimul...

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Huvudupphovsmän: Tang, Li-xia, He, Rui-hua, Yang, Guang, Tan, Jia-ju, Zhou, Li, Meng, Xiao-ming, Huang, Xiao Ru, Lan, Hui Yao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280334/
https://ncbi.nlm.nih.gov/pubmed/22363627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031350
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