Homeodomain Proteins Directly Regulate ATM Kinase Activity

Ataxia-telangiectasia mutated (ATM) is a serine/threonine kinase that coordinates the response to DNA double-strand breaks and oxidative stress. NKX3.1, a prostate-specific transcription factor, was recently shown to directly stimulate ATM kinase activity through its highly conserved homeodomain. He...

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Publicado no:Cell Rep
Main Authors: Johnson, Tanya E., Lee, Ji-Hoon, Myler, Logan R., Zhou, Yi, Mosley, Trenell J., Yang, Soo-Hyun, Uprety, Nadima, Kim, Jonghwan, Paull, Tanya T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127865/
https://ncbi.nlm.nih.gov/pubmed/30089259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.089
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