A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α(v)β(3) integrin for osteoporosis therapy

There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide. We have developed a combinatorial strategy for engineering bispecific inhibitors that simultaneously target the unique combination of c-FMS an...

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Detalles Bibliográficos
Publicado en:PLoS Biol
Main Authors: Zur, Yuval, Rosenfeld, Lior, Keshelman, Chen Anna, Dalal, Nofar, Guterman-Ram, Gali, Orenbuch, Ayelet, Einav, Yulia, Levaot, Noam, Papo, Niv
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126843/
https://ncbi.nlm.nih.gov/pubmed/30142160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002979
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