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A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α(v)β(3) integrin for osteoporosis therapy
There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide. We have developed a combinatorial strategy for engineering bispecific inhibitors that simultaneously target the unique combination of c-FMS an...
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| Vydáno v: | PLoS Biol |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6126843/ https://ncbi.nlm.nih.gov/pubmed/30142160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002979 |
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