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Automated screening for small organic ligands using DNA-encoded chemical libraries
DNA-encoded chemical libraries (DECLs) are collections of organic compounds, which are individually linked to different oligonucleotides, serving as amplifiable identification barcodes. Since all compounds in the library can be identified by their DNA tag, they can be mixed and used in affinity capt...
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| Pubblicato in: | Nat Protoc |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6126613/ https://ncbi.nlm.nih.gov/pubmed/26985574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.039 |
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