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Monitoring PARKIN RBR Ubiquitin Ligase Activation States with UbFluor
PARKIN is a RING-Between-RING (RBR) E3 ligase, which ubiquitinates mitochondrial proteins in response to mitochondrial damage. Ser(65) of PARKIN is phosphorylated by kinase PINK1 (pPARKIN), which causes partial PARKIN activation. PINK1 also phosphorylates Ser(65) of ubiquitin (pUb), which activates...
Gorde:
| Argitaratua izan da: | Curr Protoc Chem Biol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125222/ https://ncbi.nlm.nih.gov/pubmed/30063295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.45 |
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