Φορτώνει......
Parkin-phosphoubiquitin complex reveals a cryptic ubiquitin binding site required for RBR ligase activity
RING-BETWEENRING-RING (RBR) E3 ligases are a class of ubiquitin ligases distinct from RING or HECT E3 ligases. An important RBR is Parkin, mutations in which lead to early onset hereditary Parkinsonism. Parkin and other RBRs share a catalytic RBR module, but are usually autoinhibited and activated v...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Struct Mol Biol |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5420311/ https://ncbi.nlm.nih.gov/pubmed/28414322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3400 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|