Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

Recent advances in the management of cystic fibrosis (CF) target underlying defects in the CF transmembrane conductance regulator (CFTR) protein, but efficacy analyses remain limited to specific genotype–based subgroups. Patient-derived model systems may therefore aid in expanding access to these dr...

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Vydáno v:JCI Insight
Hlavní autoři: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Technical Advance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124537/
https://ncbi.nlm.nih.gov/pubmed/29997283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99385
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