Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

Recent advances in the management of cystic fibrosis (CF) target underlying defects in the CF transmembrane conductance regulator (CFTR) protein, but efficacy analyses remain limited to specific genotype–based subgroups. Patient-derived model systems may therefore aid in expanding access to these dr...

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Опубликовано в: :JCI Insight
Главные авторы: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124537/
https://ncbi.nlm.nih.gov/pubmed/29997283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99385
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