Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

Recent advances in the management of cystic fibrosis (CF) target underlying defects in the CF transmembrane conductance regulator (CFTR) protein, but efficacy analyses remain limited to specific genotype–based subgroups. Patient-derived model systems may therefore aid in expanding access to these dr...

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
Schlagworte:
Technical Advance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124537/
https://ncbi.nlm.nih.gov/pubmed/29997283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99385
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