Detection of CFTR function and modulation in primary human nasal cell spheroids

BACKGROUND: Expansion of CFTR modulators to patients with rare/undescribed mutations will be facilitated by patient-derived models quantifying CFTR function and restoration. We aimed to generate a personalized model system of CFTR function and modulation using non-surgically obtained nasal epithelia...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cyst Fibros
Egile Nagusiak: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Ostmann, Alicia J., Strecker, Lauren M., Szczesniak, Rhonda D., Clancy, John P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868354/
https://ncbi.nlm.nih.gov/pubmed/28712885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2017.06.010
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