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Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

Recent advances in the management of cystic fibrosis (CF) target underlying defects in the CF transmembrane conductance regulator (CFTR) protein, but efficacy analyses remain limited to specific genotype–based subgroups. Patient-derived model systems may therefore aid in expanding access to these dr...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124537/
https://ncbi.nlm.nih.gov/pubmed/29997283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99385
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