Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

Recent advances in the management of cystic fibrosis (CF) target underlying defects in the CF transmembrane conductance regulator (CFTR) protein, but efficacy analyses remain limited to specific genotype–based subgroups. Patient-derived model systems may therefore aid in expanding access to these dr...

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Foilsithe in:JCI Insight
Main Authors: Brewington, John J., Filbrandt, Erin T., LaRosa, F.J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2018
Ábhair:
Technical Advance
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124537/
https://ncbi.nlm.nih.gov/pubmed/29997283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99385
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