Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq

A central challenge in oncology is how to kill tumors containing heterogeneous cell populations defined by different combinations of mutated genes. Identifying these mutated genes and understanding how they cooperate requires single-cell analysis, but current single-cell analytic methods, such as PC...

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Bibliografiset tiedot
Julkaisussa:Nat Biotechnol
Päätekijät: Mann, Karen M, Newberg, Justin Y, Black, Michael A, Jones, Devin J, Amaya-Manzanares, Felipe, Guzman-Rojas, Liliana, Kodama, Takahiro, Ward, Jerrold M, Rust, Alistair G, van der Weyden, Louise, Kuan Yew, Christopher Chin, Waters, Jill L, Leung, Marco L, Rogers, Keith, Rogers, Susan M, McNoe, Leslie A, Selvanesan, Luxmanan, Navin, Nicholas, Jenkins, Nancy A, Copeland, Neal G, Mann, Michael B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124494/
https://ncbi.nlm.nih.gov/pubmed/27479497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3637
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