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The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures

The EphA2 receptor tyrosine kinase is capable of activating multiple diverse signaling pathways with roles in processes such as tissue homeostasis and cancer. EphA2 is known to form activated oligomers in the presence of ephrin-A ligands. Here, we characterize the lateral interactions between full-l...

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Pubblicato in:Commun Biol
Autori principali: Singh, Deo R., Kanvinde, Pranjali, King, Christopher, Pasquale, Elena B., Hristova, Kalina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123813/
https://ncbi.nlm.nih.gov/pubmed/30271902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0017-7
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