Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions

The quality control testing of chemical degradations in the bio-pharmaceutical industry is currently under controversial debate. Here we have systematically applied in vitro and in vivo stress conditions to investigate the influence of protein degradation on structure-function. Extensive purificatio...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Commun Biol
Autors principals: Schmid, Ingrid, Bonnington, Lea, Gerl, Monika, Bomans, Katrin, Thaller, Anna Louisa, Wagner, Katharina, Schlothauer, Tilman, Falkenstein, Roberto, Zimmermann, Boris, Kopitz, Jürgen, Hasmann, Max, Bauss, Frieder, Haberger, Markus, Reusch, Dietmar, Bulau, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123738/
https://ncbi.nlm.nih.gov/pubmed/30271914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0032-8
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars