Chargement en cours...
Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis
In cytokinesis with chromatin bridges, cells delay abscission and retain actin patches at the intercellular canal to prevent chromosome breakage. In this study, we show that inhibition of Src, a protein-tyrosine kinase that regulates actin dynamics, or Chk1 kinase correlates with chromatin breakage...
Enregistré dans:
| Publié dans: | J Cell Biol |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6122982/ https://ncbi.nlm.nih.gov/pubmed/29954829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802102 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|