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The voltage-gated sodium channel pore exhibits conformational flexibility during slow inactivation
Slow inactivation in voltage-gated sodium channels (Na(V)s) directly regulates the excitability of neurons, cardiac myocytes, and skeletal muscles. Although Na(V) slow inactivation appears to be conserved across phylogenies—from bacteria to humans—the structural basis for this mechanism remains uncl...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6122925/ https://ncbi.nlm.nih.gov/pubmed/30082431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812118 |
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