Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer

Head and neck squamous cell carcinoma (HNSCC) is the 6th most common human cancer and affects approximately 50,000 new patients every year in the US. The major risk factors for HNSCC are tobacco and alcohol consumption as well as oncogenic HPV infections. Despite advances in therapy, the overall sur...

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Udgivet i:Front Oncol
Main Authors: Bisetto, Sara, Whitaker-Menezes, Diana, Wilski, Nicole A., Tuluc, Madalina, Curry, Joseph, Zhan, Tingting, Snyder, Christopher M., Martinez-Outschoorn, Ubaldo E., Philp, Nancy J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120975/
https://ncbi.nlm.nih.gov/pubmed/30211114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00324
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