Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer

Here, we interrogated head and neck cancer (HNSCC) specimens (n = 12) to examine if different metabolic compartments (oxidative vs. glycolytic) co-exist in human tumors. A large panel of well-established biomarkers was employed to determine the metabolic state of proliferative cancer cells. Interest...

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Detalhes bibliográficos
Principais autores: Curry, Joseph M., Tuluc, Madalina, Whitaker-Menezes, Diana, Ames, Julie A., Anantharaman, Archana, Butera, Aileen, Leiby, Benjamin, Cognetti, David M., Sotgia, Federica, Lisanti, Michael P., Martinez-Outschoorn, Ubaldo E.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674065/
https://ncbi.nlm.nih.gov/pubmed/23574725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24092
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