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Cancer Metabolism: New Validated Targets for Drug Discovery

Recent studies in cancer metabolism directly implicate catabolic fibroblasts as a new rich source of i) energy and ii) biomass, for the growth and survival of anabolic cancer cells. Conversely, anabolic cancer cells upregulate oxidative mitochondrial metabolism, to take advantage of the abundant fib...

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Detalhes bibliográficos
Main Authors: Sotgia, Federica, Martinez-Outschoorn, Ubaldo E., Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787159/
https://ncbi.nlm.nih.gov/pubmed/23896568
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