MCT1 in Invasive Ductal Carcinoma: Monocarboxylate Metabolism and Aggressive Breast Cancer

Introduction: Monocarboxylate transporter 1 (MCT1) is an importer of monocarboxylates such as lactate and pyruvate and a marker of mitochondrial metabolism. MCT1 is highly expressed in a subgroup of cancer cells to allow for catabolite uptake from the tumor microenvironment to support mitochondrial...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Johnson, Jennifer M., Cotzia, Paolo, Fratamico, Roberto, Mikkilineni, Lekha, Chen, Jason, Colombo, Daniele, Mollaee, Mehri, Whitaker-Menezes, Diana, Domingo-Vidal, Marina, Lin, Zhao, Zhan, Tingting, Tuluc, Madalina, Palazzo, Juan, Birbe, Ruth C., Martinez-Outschoorn, Ubaldo E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376582/
https://ncbi.nlm.nih.gov/pubmed/28421181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00027
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