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A novel multifunctional anti-CEA-IL15 molecule displays potent antitumor activities

INTRODUCTION: Interleukin-15 (IL-15) is an immunomodulatory cytokine. It can activate and expand cytotoxic CD8 T lymphocytes and natural killer cells, leading to potent antitumor effects. Various forms of IL-15 are now in different stages of development for cancer immunotherapy. One of the major iss...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: Liu, Yue, Wang, Yanlan, Xing, Jieyu, Li, Yumei, Liu, Jiayu, Wang, Zhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120566/
https://ncbi.nlm.nih.gov/pubmed/30214153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S166373
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