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A novel multifunctional anti-CEA-IL15 molecule displays potent antitumor activities
INTRODUCTION: Interleukin-15 (IL-15) is an immunomodulatory cytokine. It can activate and expand cytotoxic CD8 T lymphocytes and natural killer cells, leading to potent antitumor effects. Various forms of IL-15 are now in different stages of development for cancer immunotherapy. One of the major iss...
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| Gepubliceerd in: | Drug Des Devel Ther |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Dove Medical Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120566/ https://ncbi.nlm.nih.gov/pubmed/30214153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S166373 |
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