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A targeted IL-15 fusion protein with potent anti-tumor activity
IL-15 has been actively investigated for its potential in tumor immunotherapy. To enhance the anti-tumor activity of IL-15, the novel PFC-1 construct was designed, which comprises the following 3 parts: (1) IL-15Rα fused with IL-15 to enhance IL-15 activity, (2) an Fc fragment to increase protein ha...
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| Publicado no: | Cancer Biol Ther |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622986/ https://ncbi.nlm.nih.gov/pubmed/26176990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071739 |
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