A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity

This protocol describes the construction and functional studies of a bispecific antibody (bsAb), GPC3-S-Fab. bsAbs can recognize two different epitopes through their two different arms. bsAbs have been actively studied for their ability to directly recruit immune cells to kill tumor cells. Currently...

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Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Wang, Yanlan, Liu, Jiayu, Pan, Haitao, Xing, Jieyu, Wu, Xiaoqiong, Li, Qing, Wang, Zhong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2018
Konular:
Cancer Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126450/
https://ncbi.nlm.nih.gov/pubmed/30059039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57588
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