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Site-specific PEGylation of an anti-CEA/CD3 bispecific antibody improves its antitumor efficacy
INTRODUCTION: Bispecific antibodies that engage immune cells to kill cancer cells are actively pursued in cancer immunotherapy. Different types of bispecific antibodies, including single-chain fragments, Fab fragments, nanobodies, and immunoglobulin Gs (IgGs), have been studied. However, the low mol...
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| Veröffentlicht in: | Int J Nanomedicine |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985803/ https://ncbi.nlm.nih.gov/pubmed/29881272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S164542 |
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