Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies

CD16a (FcγRIIIa) mediates the antibody dependent cellular cytotoxicity (ADCC) and is important for anti-tumor activities of many therapeutic antibodies. Bispecific antibody targeting natural killer (NK) cells has been studied for cancer therapy. In this work, anti-CD16a single-domain antibodies were...

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發表在:Cancer Biol Ther
Main Authors: Zhao, Yining, Li, Yumei, Wu, Xiaoqiong, Li, Li, Liu, Jiayu, Wang, Yanlan, Liu, Yue, Li, Qing, Wang, Zhong
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2019
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012161/
https://ncbi.nlm.nih.gov/pubmed/31564196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1665953
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