RNA ligase-like domain in activating signal cointegrator 1 complex subunit 1 (ASCC1) regulates ASCC complex function during alkylation damage

Multiple DNA damage response (DDR) pathways have evolved to sense the presence of damage and recruit the proper repair factors. We recently reported a signaling pathway induced upon alkylation damage to recruit the AlkB homolog 3, α-ketoglutarate–dependent dioxygenase (ALKBH3)–activating signal coin...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Soll, Jennifer M., Brickner, Joshua R., Mudge, Miranda C., Mosammaparast, Nima
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120213/
https://ncbi.nlm.nih.gov/pubmed/29997253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000114
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