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Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase
Repair of DNA alkylation damage is critical for genomic stability and involves multiple conserved enzymatic pathways. Alkylation damage resistance, which is critical in cancer chemotherapy, depends on the overexpression of alkylation repair proteins. However, the mechanisms responsible for this upre...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475402/ https://ncbi.nlm.nih.gov/pubmed/25944111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490497 |
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