OTUD4 is a phospho-activated K63 deubiquitinase that regulates MyD88-dependent signaling

Ubiquitination is a major mechanism that regulates numerous cellular processes, including autophagy, DNA damage signaling, and inflammation. While hundreds of ubiquitin ligases exist to conjugate ubiquitin onto substrates, approximately one hundred deubiquitinases are encoded by the human genome. Th...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Zhao, Yu, Mudge, Miranda C., Soll, Jennifer M., Rodrigues, Rachel B., Byrum, Andrea K., Schwarzkopf, Elizabeth A., Bradstreet, Tara R., Gygi, Steven P., Edelson, Brian T., Mosammaparast, Nima
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819006/
https://ncbi.nlm.nih.gov/pubmed/29395066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.009
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