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OTUD4 is a phospho-activated K63 deubiquitinase that regulates MyD88-dependent signaling
Ubiquitination is a major mechanism that regulates numerous cellular processes, including autophagy, DNA damage signaling, and inflammation. While hundreds of ubiquitin ligases exist to conjugate ubiquitin onto substrates, approximately one hundred deubiquitinases are encoded by the human genome. Th...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6819006/ https://ncbi.nlm.nih.gov/pubmed/29395066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.009 |
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