OTUD4 is a phospho-activated K63 deubiquitinase that regulates MyD88-dependent signaling

Ubiquitination is a major mechanism that regulates numerous cellular processes, including autophagy, DNA damage signaling, and inflammation. While hundreds of ubiquitin ligases exist to conjugate ubiquitin onto substrates, approximately one hundred deubiquitinases are encoded by the human genome. Th...

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Publicado en:Mol Cell
Autores principales: Zhao, Yu, Mudge, Miranda C., Soll, Jennifer M., Rodrigues, Rachel B., Byrum, Andrea K., Schwarzkopf, Elizabeth A., Bradstreet, Tara R., Gygi, Steven P., Edelson, Brian T., Mosammaparast, Nima
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819006/
https://ncbi.nlm.nih.gov/pubmed/29395066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.009
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