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A 1 week IGF‐1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep

Fetal insulin is critical for regulation of growth. Insulin concentrations are partly determined by the amount of β‐cells present and their insulin content. Insulin‐like growth factor‐1 (IGF‐1) is a fetal anabolic growth factor which also impacts β‐cell mass in models of β‐cell injury and diabetes....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Physiol Rep
Päätekijät: White, Alicia, Louey, Samantha, Chang, Eileen I, Boehmer, Brit H., Goldstrohm, David, Jonker, Sonnet S., Rozance, Paul J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119661/
https://ncbi.nlm.nih.gov/pubmed/30175552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13840
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