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Chronic Fetal Leucine Infusion Does Not Potentiate Glucose-Stimulated Insulin Secretion or Affect Pancreatic Islet Development in Late-Gestation Growth-Restricted Fetal Sheep

BACKGROUND: Growth-restricted fetuses have attenuated glucose-stimulated insulin secretion (GSIS), smaller pancreatic islets, less pancreatic β-cells, and less pancreatic vascularization compared with normally growing fetuses. Infusion of leucine into normal late-gestation fetal sheep potentiates GS...

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Detalhes bibliográficos
Publicado no:J Nutr
Main Authors: Boehmer, Brit H, Wesolowski, Stephanie R, Brown, Laura D, Rozance, Paul J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850025/
https://ncbi.nlm.nih.gov/pubmed/33326574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxaa357
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