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IGF-1 infusion to fetal sheep increases organ growth but not by stimulating nutrient transfer to the fetus

Insulin-like growth factor-1 (IGF-1) is an important fetal growth factor. However, the role of fetal IGF-1 in increasing placental blood flow, nutrient transfer, and nutrient availability to support fetal growth and protein accretion is not well understood. Catheterized fetuses from late gestation p...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Stremming, Jane, Heard, Sara, White, Alicia, Chang, Eileen I., Shaw, Steven C., Wesolowski, Stephanie R., Jonker, Sonnet S., Rozance, Paul J., Brown, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988781/
https://ncbi.nlm.nih.gov/pubmed/33427051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00453.2020
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