Identification of Helicobacter pylori VacA in Human Lung and its Effects on Lung Cells

OBJECTIVE: Prior reports suggested that infection with Helicobacter pylori was associated with respiratory diseases; pathogenetic mechanisms however, were not defined. We tested the hypothesis that VacA, an exotoxin of Helicobacter pylori, a gastric pathogen, was aspirated into the lung and could st...

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Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Nakashima, Shota, Kakugawa, Tomoyuki, Yura, Hirokazu, Tomonaga, Masaomi, Harada, Tatsuhiko, Hara, Atsuko, Hara, Shintaro, Nakano, Masayuki, Yamasaki, Eiki, Sakamoto, Noriho, Ishimatsu, Yuji, Isomoto, Hajime, Gochuico, Bernadette R., Suffredini, Anthony F., Mukae, Hiroshi, Kurazono, Hisao, Hirayama, Toshiya, Moss, Joel, Kohno, Shigeru
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118350/
https://ncbi.nlm.nih.gov/pubmed/25817795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.03.096
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